Prostaglandins are short-lived, hormone-like compounds that our bodies make in a series of steps from the two essential fats, cis-linoleic acid (omega-6) and sis-linolenic acid (omega-3). 85% of the US population is now deficient in omega-3 essential fats, because modern methods of food processing have destroyed most of them in the food chain. The amount of essential fats required for health is 6-10gms/day (larger by far than for any vitamin or mineral). Athletes require even more because of the multiple uses of essential fats during exercise. Prostaglandins regulate every cell, every organ and every bodily function – therefore the right amount of essential fatty acids are crucial for proper prostaglandin functioning!. There are more than 50 different types of prostaglandins. Problems in their production result in disease, like cancer, asthma, allergies and autoimmune diseases like rheumatoid arthritis, lupus. If a prostaglandin imbalance is suspected, the first thing to look for is whether they are getting enough EFAs (linoleic acid (LA) and linolenic acid (LNA). The second culprit to look for is a deficiency in the key co-factor vitamins and minerals (Vit A, B-6, C and E and magnesium, zinc, copper and selenium), that make it possible for enzymes to regulate the metabolism of LA and LNA.