Cis- and trans fatty acids
“Trans” and “cis” refer to whether the ends of the fatty acid molecule are on the same side of the double bond (cis) or on opposite sides of the double bond (trans).
The half –life of cis fatty acids is 18 days – therefore the turnover of naturally occurring fatty acids is less than 3 weeks. In chronic patients, making changes with EFA supplementation often takes at least three weeks. A common therapy for hot flashes in women, has been a multiple EFA product taken for three weeks.
The half-life of trans fatty acids is 51 days – half of the bad fats from the potato chip you eat today are still in your body two months from now!